Diet and Microbiota

The human gastrointestinal tract is the home for trillions of bacteria that are continuously shaped by different factors and amongst these factors is the particular dietary habit followed.

Maternal obesity and the gut microbiome

Maternal Obesity and the Gut Microbiome Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020​ Maternal obesity is the result of complex and multifactorial pathways and is associated with multiple pregnancy complications such as increased risk of miscarriage, gestational diabetes, hypertension, and preeclampsia as well as increased risk of cesarean section delivery. Maternal obesity is the […]

Nutritional recommendations for the perinatal period and influence on infant gut microbiota development

Nutritional Recommendations for the Perinatal Period and Influence on Infant Gut Microbiota Development Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020​ Purpose of the reviewed article: Highlight the nutritional recommendations for perinatal period (perinatal period starts at 22 completed weeks of gestation and ends 7 completed days after birth) The influence of maternal microbiome and […]

The importance of the first 1000 days of life on microbiota development

The Importance of the First 1000 Days of Life on Microbiota Development Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020​ Scientific evidence confirms that the early period of human life that begins at conception and continue until 24 months of life (also called the first 1000 days of life ) plays a vital role for […]

The associations of maternal pre-pregnancy BMI with pregnancy and infant gut microbiome

The Associations of Maternal Pre-Pregnancy Body Mass Index with Pregnancy and Infant Gut Microbiome (Michigan Study) Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020​ This study was conducted by researchers from Michigan State University to investigate the association between BMI before pregnancy and gut microbiota in late pregnancy (mothers) and early infancy (babies). Researchers investigated […]

Microbiome before pregnancy and its impact on successful conception

Microbiome Before Pregnancy and its Impact on Successful Conception Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020​ It has been assumed that the composition of microbiota of follicular fluid, semen, uterine and vagina before pregnancy contribute to a successful pregnancy (1): Microbiota in the follicular fluid was found to play an important role in the […]

Maternal gut microbiota changes and periconceptional diet

Maternal Gut Microbiota Changes and Periconceptional Diet Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020​ Manipulation of maternal diet during pre-pregnancy and pregnancy has been identified to impact fetal growth and development as a result of change in intrauterine environment (1). In animal models, intrauterine growth restriction has been found to alter neonatal gut microbiota […]

Ethnic background and vaginal microbiota

Ethnic Background and Vaginal Microbiota Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020​ The vaginal microbiota is complex ecosystem influenced by ethnic background, genes, and environmental and behavioural factors. The healthy vagina is dominated by several Lactobacillus species that support the defence system against infection and dysbiosis (an imbalance in the microbial community that is […]

Preterm birth and vaginal microbiome

The Vaginal Microbiome and Preterm Birth Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020​ Preterm birth is defined as “babies born alive before 37 weeks of pregnancy completed”. Every year, about 15 million babies are born prematurely worldwide and 1 in 10 families around the world are affected by the birth of preterm babies. More […]