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MothersBabies Newsletter:

The Microbiome and Your Fertility: A Review of the Science

22/9/2025

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The topic of microbiome health and fertility is growing in popularity and importance, as we delve deeper into exactly what it means for reproduction and how we might be able to make this relatively new information work in our favour…

Let’s look at some of the points from a 2023 scientific review on the topic of how the microbiome can impact your fertility…

  • Previous studies focusing on mothers and babies during the perinatal period have shown frequent microbial interactions and transmission across various body sites, indicating the importance of microbial homeostasis, particularly in the gut and reproductive tract, for the health of both mothers and infants during this critical time window.
  • Emerging studies suggest that the depletion of certain bacteria in early life may lead to significant health issues in childhood.
  • Some studies have suggested the existence of microbiome–gut–vagina axis, leading to the intervention using probiotics to rehabilitate gut microbiota homeostasis and thereby improve reproductive health.
  • An unhealthy lifestyle during pregnancy disturbs the maternal microbiome, which is associated with poor maternal conditions and leads to the occurrence of pregnancy complications, further influencing the development of infants. 
  • Recent studies have associated the microbiome in the female reproductive tract (FRT) with assisted reproductive technology (ART) outcomes, and restoring microbiome balance has been shown to improve fertility in infertile couples.

Overall, this review really highlights the importance of developing healthy habits before and during pregnancy as this is associated with a more well-balanced microbiome, and a higher chance of positive pregnancy outcomes.

If you are interested in reading the full review, click here.

Reference: Xiao L, Zuo Z, Zhao F. Microbiome in Female Reproductive Health: Implications for Fertility and Assisted Reproductive Technologies. Genomics, Proteomics & Bioinformatics. 2023 Dec 13:qzad005.

In our online course ‘Healthy Gut, Healthier Baby’, (which is currently FREE!) we go into some specific factors that you can focus on in order to optimise your various microbiomes for fertility. 

Our Pre-Pregnancy Bundle includes modules on prepping for pregnancy, probiotics, prebiotics, gut health and diet, and the importance of nurturing your microbes to fuel your fertility.


The Pre-Pregnancy Bundle
•   Module 2
Fertility Curiosity – Learn about fertility and genetic testing you have access to, fertility decline, and how to best nurture your body for your future pregnancy.

•   Module 3
Gut Health for Future Generations – Learn about the importance of your gut microbiome in fertility, pregnancy, and for future bub’s health.

•   Module 4
Pre-Pregnancy Planning – Learn to actively prepare for a healthy pregnancy and make appropriate diet and lifestyle adjustments.


If you’d like to find out more about the impact that your diet and lifestyle can have on your fertility, plus so much more, why not check out our entire online course ‘Healthy Gut, Healthier Baby’?

It is FREE for a limited time!
Comment ‘HEALTHYBUB’ at checkout to gain free access today!

The information in this newsletter is provided for general educational purposes only.

Statements or opinions expressed in the newsletter should not be taken as fact, but as opinion on the current state of evidence based science. The content is not (and should not be taken to be) medical advice or an endorsement or recommendation of any specific product or treatment. 

If you require medical attention please seek professional advice from an appropriately experienced health practitioner.

 

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