Findings from the American Gut Project
Findings from the American Gut Project Written by Dr Fathalla Ali, PhD Paediatrics 06/12/2021 The first major data of the human microbiome was generated from the American Gut project (AGP). The project included microbial data from 15,096 samples that were collected from 11,336 participants, primarily resident in the United States, United Kingdom, Australia and other […]
The persistent gut microbiota in infancy and it’s origin
The Persistent Gut Microbiota in Infancy and it’s Origin Scientifically reviewed by Dr Fathalla Ali, PhD (Paediatrics) 29/11/2021 During and after birth, the gut of a newborn baby is rapidly colonized with microbiota. This early gut colonization plays an important role in the baby’s immune system development. Factors such as premature birth, cesarean section delivery […]
The early life determinants for Gut Dysbiosis
The early life determinants for Gut Dysbiosis Written by Dr Fathalla Ali, PhD (Paedatrics) 22/11/2021 The gastrointestinal tract is the home for the most diverse and populated bacterial community known as microbiota. Ideally, the gut microbiota lives in a mutually symbiotic relationship with the human body. Whilst the gut provides the well-adapted shelter, the microbiota […]
The introduction to solid foods and gut microbiota stability
The first 1-3 years of life is an important period for the development of our gut microbiota. During this critical time, gut microbiota development progresses from it being a relatively simple microbial community that is less rich and diverse, to a one that is high in richness and diversity.
Diet and Microbiota
The human gastrointestinal tract is the home for trillions of bacteria that are continuously shaped by different factors and amongst these factors is the particular dietary habit followed.
Breastfeeding and the infant gut microbiota at 12 months of age
Feeding human milk to newborn infants has important nutritional, physiological, immunological and psychological benefits that may impact on their long-term growth and development.
The Persistent Effects of Birth Mode on Gut Microbiota Composition, Immune System Development and Antimicrobial Resistance
It is believed that mode of birth (Vaginal or Caesarean) has a significant effect on early gut microbiota acquisition and development. Globally, the rate of caesarean birth is consistently increasing as a result of multiple factors. Among these factors are the increase in the overall income and the easy access to health facilities. In 2015, around 29.7 million births happened by caesarean, accounting for about 18% of the births in 169 countries.
Early Microbiota Colonization and Gut Metabolome
It’s believed that the status of our health in later life is associated with the first bacteria that colonize our gut.
High Fat Diet, Obesity and Microbiota
Nutrition during pregnancy is one of the most important factors that play a significant role in the early developmental process through the regulation of epigenetic mechanisms during pregnancy and neonatal periods.
The role of Bifidobacteria in HMOs utilization and systematic immune upregulation
Among the most abundant members of the gut microbiota that colonize the gut of infants during early days of life are Bifidobacteria, which are believed to play a major role in the development of the immune system
