Excerpt from The First Thousand Days: An Evidence Paper
Excerpt from ‘The First Thousand Days: An Evidence Paper’ Section 3.2.1 The role of the microbiome Written by The Centre for Community Child Health The Royal Children’s Hospital Melbourne September 2017 Vast numbers of bacteria, viruses, and fungi (collectively known as the microbiome) live in and on the human body and play an important role […]
The early life determinants for Gut Dysbiosis
The early life determinants for Gut Dysbiosis Written by Dr Fathalla Ali, PhD (Paedatrics) 22/11/2021 The gastrointestinal tract is the home for the most diverse and populated bacterial community known as microbiota. Ideally, the gut microbiota lives in a mutually symbiotic relationship with the human body. Whilst the gut provides the well-adapted shelter, the microbiota […]
The introduction to solid foods and gut microbiota stability
The first 1-3 years of life is an important period for the development of our gut microbiota. During this critical time, gut microbiota development progresses from it being a relatively simple microbial community that is less rich and diverse, to a one that is high in richness and diversity.
Diet and Microbiota
The human gastrointestinal tract is the home for trillions of bacteria that are continuously shaped by different factors and amongst these factors is the particular dietary habit followed.
Breastfeeding and the infant gut microbiota at 12 months of age
Feeding human milk to newborn infants has important nutritional, physiological, immunological and psychological benefits that may impact on their long-term growth and development.
The Persistent Effects of Birth Mode on Gut Microbiota Composition, Immune System Development and Antimicrobial Resistance
It is believed that mode of birth (Vaginal or Caesarean) has a significant effect on early gut microbiota acquisition and development. Globally, the rate of caesarean birth is consistently increasing as a result of multiple factors. Among these factors are the increase in the overall income and the easy access to health facilities. In 2015, around 29.7 million births happened by caesarean, accounting for about 18% of the births in 169 countries.
Early Microbiota Colonization and Gut Metabolome
It’s believed that the status of our health in later life is associated with the first bacteria that colonize our gut.
High Fat Diet, Obesity and Microbiota
Nutrition during pregnancy is one of the most important factors that play a significant role in the early developmental process through the regulation of epigenetic mechanisms during pregnancy and neonatal periods.
The role of Bifidobacteria in HMOs utilization and systematic immune upregulation
Among the most abundant members of the gut microbiota that colonize the gut of infants during early days of life are Bifidobacteria, which are believed to play a major role in the development of the immune system
90% of infants lack bacterial species needed for immune system development
A multiple states metagenomic cross sectional study revealed that the vast majority of American infants showed a significant deficiency in an important bacterial strain essential for human milk utilization and immune system development.