The first glimpse of the endometrial microbiota in early pregnancy

The First Glimpse of the Endometrial Microbiota in Early Pregnancy Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020​ A research team from the Universitat de València, in collaboration with the Igenomix Foundation and INCLIVA, for the first time has managed to describe the structure and function of human endometrial (the mucous layer that lines the […]

The importance of the first 1000 days of life on microbiota development

The Importance of the First 1000 Days of Life on Microbiota Development Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020​ Scientific evidence confirms that the early period of human life that begins at conception and continue until 24 months of life (also called the first 1000 days of life ) plays a vital role for […]

The associations of maternal pre-pregnancy BMI with pregnancy and infant gut microbiome

The Associations of Maternal Pre-Pregnancy Body Mass Index with Pregnancy and Infant Gut Microbiome (Michigan Study) Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020​ This study was conducted by researchers from Michigan State University to investigate the association between BMI before pregnancy and gut microbiota in late pregnancy (mothers) and early infancy (babies). Researchers investigated […]

Microbiome before pregnancy and its impact on successful conception

Microbiome Before Pregnancy and its Impact on Successful Conception Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020​ It has been assumed that the composition of microbiota of follicular fluid, semen, uterine and vagina before pregnancy contribute to a successful pregnancy (1): Microbiota in the follicular fluid was found to play an important role in the […]

Maternal gut microbiota changes and periconceptional diet

Maternal Gut Microbiota Changes and Periconceptional Diet Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020​ Manipulation of maternal diet during pre-pregnancy and pregnancy has been identified to impact fetal growth and development as a result of change in intrauterine environment (1). In animal models, intrauterine growth restriction has been found to alter neonatal gut microbiota […]

Ethnic background and vaginal microbiota

Ethnic Background and Vaginal Microbiota Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020​ The vaginal microbiota is complex ecosystem influenced by ethnic background, genes, and environmental and behavioural factors. The healthy vagina is dominated by several Lactobacillus species that support the defence system against infection and dysbiosis (an imbalance in the microbial community that is […]

Microbiome and microbiota – definition and history

Microbiome and Microbiota – Defintion & History Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020​ Advancement the in the DNA/RNA analysis and computing technologies has transformed the field of microbial community analysis. This advancement has accompanied by rapid increase in the number of researches describing the composition, structure and function of microbial communities that inhabiting […]

Preterm birth and vaginal microbiome

The Vaginal Microbiome and Preterm Birth Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020​ Preterm birth is defined as “babies born alive before 37 weeks of pregnancy completed”. Every year, about 15 million babies are born prematurely worldwide and 1 in 10 families around the world are affected by the birth of preterm babies. More […]

Differences in the fecal microbiota of neonates

Differences in the Fecal Microbiota of Neonates Born at Home or in the Hospital Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020 Many factors have been identified that alter the process of human microbiota development in early life. The prenatal, antenatal and postnatal period have been found to be the most developmentally sensitive times. The […]

Bifidobacteria supplementation in preventing allergy development in infants

Bifidobacteria Supplementation in Preventing Allergy Development in Infants Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020 The World Health Organization (WHO) and the Food and Agriculture Organization (FAO) defines a “probiotic” as “live microorganisms which, when ingested in an adequate amount as part of foods, benefit the health of the host” (FAO & WHO). It […]