The Persistent Effects of Birth Mode on Gut Microbiota Composition, Immune System Development and Antimicrobial Resistance
It is believed that mode of birth (Vaginal or Caesarean) has a significant effect on early gut microbiota acquisition and development. Globally, the rate of caesarean birth is consistently increasing as a result of multiple factors. Among these factors are the increase in the overall income and the easy access to health facilities. In 2015, around 29.7 million births happened by caesarean, accounting for about 18% of the births in 169 countries.
Early Microbiota Colonization and Gut Metabolome
It’s believed that the status of our health in later life is associated with the first bacteria that colonize our gut.
High Fat Diet, Obesity and Microbiota
Nutrition during pregnancy is one of the most important factors that play a significant role in the early developmental process through the regulation of epigenetic mechanisms during pregnancy and neonatal periods.
The role of Bifidobacteria in HMOs utilization and systematic immune upregulation
Among the most abundant members of the gut microbiota that colonize the gut of infants during early days of life are Bifidobacteria, which are believed to play a major role in the development of the immune system
Breast Feeding and The Hot Topic Of Immunity
Is there a hotter topic than immunity in these Covid-19 times? As the global scientific community focuses on developing vaccines that confer immunity, we’ve become familiar with the concept of a compromised or ‘weakened’ immune systems.
90% of infants lack bacterial species needed for immune system development
A multiple states metagenomic cross sectional study revealed that the vast majority of American infants showed a significant deficiency in an important bacterial strain essential for human milk utilization and immune system development.
The phases of development of the gut microbiome in babies and children
From approximately three years of age, a child’s microbiota becomes relatively stable and continues to be so throughout their lifetime.
Changes in gut microbiota during pregnancy
During the pregnancy period unique inflammatory and immune changes alter the maternal gut function and microbiota composition as the pregnancy advances.
Is probiotic supplementation during pregnancy important for labour?
Is Probiotic Supplementation During Pregnancy Important for Labour? Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020 Adaptation of the maternal immune system to the developmental change during pregnancy is an important factor for a successful pregnancy. During this period, the immune system should remain tolerance to the fetal allograft and adapt to immune functions against […]
Factors that affect the microbiome during pregnancy
Factors that Affect the Microbiome During Pregnancy Written by Dr Fathalla Ali, PHD Paediatrics 9/9/2020 Pregnancy is a complex physiological process associated with simultaneous hormonal, immunologic, and metabolic changes, which must all be synchronized to preserve the health of both the mother and the baby. Hormonal change is one of the first changes that occurs […]